Der Unterschied zwischen frischen und verglasten Eizellen

Differences between fresh and vitrified eggs

Many patients who resort for assisted reproduction technologies, like IVF, surrogacy or PGD are often baffled with the concept of cryopreservation, vitrification and slow freezing. It is natural to get confused with peculiarities of those complicated medical procedures that seem to belong to a science-fiction movie than to our reality. How is it even possible to freeze an egg or an embryo and then warm it without causing any harm? It does sound rather fictional but modern advances in medical technologies provide such a possibility with vitrification method which is the most commonly used nowadays. 

The patients who consider using ART very often enquire about what eggs provide better results – fresh or frozen? To answer this question it is necessary to look into the freezing procedures in more detail.

What is vitrification and how is it different from slow freezing?

Generally, cryopreservation is a term for freezing cells, storing and thawing them in future. It comprises two most commonly applied methods of cooling the materials down - vitrification and slow freezing. Both methods were invented almost at the same time. The first successful slow freezing procedure was reported in 1983 and soon after that doctors have discovered that it may be successfully applied to assist in infertility treatment. In this method, the reproductive cells undergo a slow freezing procedure when the temperature decreases by 3-4 degrees per minute until it reaches -196 °C. Even though the procedure was recognized to be rather advantageous, the number of eggs and embryos that turned out to be damaged after thawing was too high. The percentage of eggs with good preserved morphology after warming was only about 56%.

Vitrification was invented in 1985, but scientists started using it for preserving human cells for later, and until 2013 it was labelled as an “experimental” procedure. But the latest studies have established that it is more beneficial for the preservation of human cells, and for this reason, vitrification has become one of the most commonly used freezing procedures. For instance, almost 80% of thawed eggs preserve their properties and morphology. This success rate is achieved by the speed of freezing – the cells freeze at high speed and the water in cells does not crystallise, i.e. the inner molecular structures are not damaged. 

Frozen eggs vs fresh eggs: is there any difference?

It could be assumed that fresh eggs are better for fertilization but the most recent studies comparing fresh and vitrified oocytes have found out that the efficiency of IVF procedure is almost the same for them both. Since vitrification does not involve crystallization of water molecules in cells, it doesn’t damage the structure of an egg and does not decrease its fertilization features.  

Egg vitrification for IVF and other related options

Egg vitrification is believed to be one of the most essential procedures in assisted reproductive technologies. Here are the most common procedures involving frozen (and fresh) eggs:

  • Fresh vs frozen donor eggs. Many clinics offer oocyte donation services. After the retrieval of eggs, they are frozen until they are used for IVF in future for infertility treatment of a recipient. Naturally, recipients may often have some concerns about using frozen donor eggs. But there are absolutely no reasons for such worries because the vitrification procedure is the safest freezing procedure that doesn’t damage cell structures and for this reason, it is used even for the preservation of embryos.
  • Frozen eggs vs fresh eggs IVF. Most of the fertility clinics use both types of eggs, but the success rate of frozen eggs fertilization depends on the freezing technique the one applies. Vitrification procedure enables a higher implantation and birth rate than a slow freezing procedure. The vitrified oocytes are as fertile as the fresh ones, but the price of IVF procedure with frozen eggs is considerably lower.
  • Saving high-quality frozen eggs for the future. In the modern world, women have more chances for personal fulfilment, and thus more and more of them decide to postpone their pregnancy for a more appropriate time at their thirties. But with time the quality of eggs naturally declines, so in order to preserve the oocytes with greater potential for the conception of a healthy child, they opt for vitrification of eggs.

So, the difference in success rate between the use of fresh and vitrified eggs is not that drastic and what is more, vitrification of eggs presents more benefits in terms of timing and price. That is why patients should not be concerned about using vitrified eggs for ARTs.

If you still have questions about the frozen eggs and fresh eggs, you may schedule a consultation with a fertility expert, who will provide you with all the answers and help you need.

Was ist die genetische Präimplantationsdiagnostik (PID)?

Was ist die genetische Präimplantationsdiagnostik (PID)?

Moderne Reproduktionstechnologien haben sich in den letzten Jahrzehnten weiterentwickelt und fortgeschritten, was...

Was sind Leihmutterschaftsverträge

Was sind Leihmutterschaftsverträge

Leihmutterschaftsprogramme erfordern die Unterzeichnung verschiedener Dokumente. Dies geschieht, um alle Verfahren...

Was ist die gestation leihmutterschaft und wie sie funktioniert?

Was ist die gestation leihmutterschaft und wie sie funktioniert?

Die gestationelle Leihmutterschaft gilt als relativ neue Methode zur Behandlung von Unfruchtbarkeit. Das erste...

Wie kann ich eine Leihmutter werden

Wie kann ich eine Leihmutter werden

Die Zahl der Paare, die beginnen, sich ihre Leihmutterschaftsmöglichkeiten in der Ukraine anzusehen, steigt...

Der Eizellspendeprozess: Was zu erwarten ist

Der Eizellspendeprozess: Was zu erwarten ist

Eizellspenderin zu werden, ist für viele Frauen sowohl eine spannende Erfahrung als auch eine große...

Wie bewertet man den Erfolg einer Leihmutterschaftsagentur

Wie bewertet man den Erfolg einer Leihmutterschaftsagentur

Der Leihmutterschaftsprozess ist eine herausfordernde und aufregende Reise für die zukünftigen Eltern....

10 häufige Fragen zur Eizellspende

10 häufige Fragen zur Eizellspende

Der Prozess der Eizellspende wirft viele Fragen sowohl bei den Empfängerinnen als auch bei den Spenderinnen...

Die Fruchtbarkeit nach einer Fehlgeburt

Die Fruchtbarkeit nach einer Fehlgeburt

Die Fruchtbarkeit ist die Fähigkeit des weiblichen oder männlichen Körpers, Empfängnis zu erreichen...

Unterschied zwischen primärer und sekundärer Unfruchtbarkeit

Unterschied zwischen primärer und sekundärer Unfruchtbarkeit

Es ist nur möglich, Unfruchtbarkeit oder Sterilität zu diagnostizieren, wenn unter den günstigen...

Anzeichen vorzeitiger Wehen

Anzeichen vorzeitiger Wehen

Vorzeitige Wehen (Frühwehen) stellen eine Bedrohung für das Leben und die Gesundheit des Babys dar. Es...

Sekundäre Unfruchtbarkeit

Sekundäre Unfruchtbarkeit

Unfruchtbarkeit ist die Störung des Fortpflanzungssystems, wenn für ein Jahr oder länger die Versuche,...

Auswirkung des Rauchens auf die Fruchtbarkeit

Auswirkung des Rauchens auf die Fruchtbarkeit

Rauchen ist eine der weitesten verbreiteten schlechten Gewohnheiten. Uns wurde über die schädliche Wirkung...

Intrauterine Insemination

Intrauterine Insemination

Künstliche Befruchtung ist in der modernen Welt nichts Ungewöhnliches. Sie hat sich in den letzten Jahrzehnten...

Alkohol und Fruchtbarkeit

Alkohol und Fruchtbarkeit

Alkoholabhängigkeit ist eines der häufigsten Probleme in der modernen Welt. Dieses Problem wird unter...

Was ist der Zusammenhang zwischen Stress und Unfruchtbarkeit

Was ist der Zusammenhang zwischen Stress und Unfruchtbarkeit

Mit jedem Jahr finden Wissenschaftler mehr Beweise, die den Zusammenhang zwischen Stress, depressionsbedingten...

Prominente, die auf Leihmutterschaft zurückgegriffen haben

Prominente, die auf Leihmutterschaft zurückgegriffen haben

Leihmutterschaft ist eine der assistierten Reproduktionstechnologien. Die Leihmutter trägt das Baby, das nicht...

Endometriosis and IVF

Endometriosis and IVF

Women who refer to a gynecologist because they can’t get conceive for a long time or who want to try IVF...

IVF success rates

IVF success rates

In vitro fertilization (IVF) is the most efficient and commonly applied type of ART. It is undoubtedly the most...

PCOS and IVF

PCOS and IVF

There are many reasons why woman’s eggs may be of poor quality or quantity. Most common causes are associated...

Pregnancy with multiples

Pregnancy with multiples

Couples, who plan on getting pregnant, often enquire about how common it is to give birth to two or three babies...

What is fertility calculator?

What is fertility calculator?

The advance of modern technologies presents a number of opportunities for women to take charge of their fertility....

Male infertility symptoms

Male infertility symptoms

The modern pace of life is extremely fast and stressful. We need to keep up with so many things and follow such...

Does age matter for fertility?

Does age matter for fertility?

How does our age affect our fertility? Age is a crucial factor affecting male and female fertility. The modern...

Egg donation in Ukraine

Egg donation in Ukraine

Egg donation in Ukraine is a trending reproductive service that is becoming more and more popular. For some patients...

Motherhood after 40

Motherhood after 40

The modern world provides women with so many great opportunities but at the same time, it may cause a lot of disappointments....

Why do people choose pregnancy in Ukraine

Why do people choose pregnancy in Ukraine

The modern world presents us with so many great opportunities, the development of the state-of-art technologies...

What is medical tourism?

What is medical tourism?

 The globalization of the modern world presents us with a wide range of opportunities for work, recreation,...

Foods that increase fertility

Foods that increase fertility

The modern pace of life is extremely demanding: we need to work much, achieve much, and we have no right to fall...

Poor ovarian reserve and IVF

Poor ovarian reserve and IVF

Women who plan to get pregnant or have faced some difficulties with fertility usually refer to reproductive clinics...

Egg freezing

Egg freezing

Egg freezing, also known as the oocyte preservation is a method of woman’s fertility preservation that allows...

How to choose the perfect donor for you

How to choose the perfect donor for you

Here are some tips how to choose the perfect donor for you:   It goes without saying that your potential...

Agency’s clients need a professional legal support

Agency’s clients need a professional legal support

Anastasia Herman law office provides the full range of effective assistance within Surrogacy, Family and Fertility...

TOP 3 common myths about pregnancy

TOP 3 common myths about pregnancy

The mother’s beauty According to a myth, girls steal away their mothers’ beauty. Of course, the truth...

Getting ready for your first visit to a fertility clinic

Getting ready for your first visit to a fertility clinic

Take some time to think over and prepare the following information before your visit: List any medications,...

Contact US

Complete the form below to start your journey right now

RESERVE DONOR

Have any questions about the program?

We can provide you with all the recommendations in your particular case.

Book an appointment with your personal care coordinator or doctor.

Book now



Registrierung Weiterlesen